IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.
Metronidazole is an antibiotic that is used to treat a wide variety of infections. It works by stopping the growth of certain bacteria and parasites.This antibiotic treats only certain bacterial and parasitic infections. It will not work for viral infections (such as common cold, flu). Using any antibiotic when it is not needed can cause it to not work for future infections.Metronidazole may also be used with other medications to treat certain stomach/intestinal ulcers caused by a bacteria (H. pylori).
how to use
Take this medication by mouth as directed by your doctor. To prevent stomach upset, take this medication with food or a full glass of water or milk. The dosage is based on your medical condition and response to treatment.For the best effect, take this antibiotic at evenly spaced times. To help you remember, take this medication at the same time(s) every day.Continue to take this medication until the full prescribed amount is finished, even if symptoms disappear after a few days. Stopping the medication too early may result in a return of the infection.Tell your doctor if your condition lasts or gets worse.
Dizziness, headache, stomach upset, nausea, vomiting, loss of appetite, diarrhea, constipation, or metallic taste in your mouth may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly.This medication may cause your urine to turn darker in color. This effect is harmless and will disappear when the medication is stopped.Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.Tell your doctor right away if you have any serious side effects, including: signs of a new infection (such as sore throat that doesn’t go away, fever), easy bruising/bleeding, stomach/abdominal pain, painful urination.Get medical help right away if you have any very serious side effects, including: unsteadiness, seizures, mental/mood changes (such as confusion), trouble speaking, numbness/tingling of arms/legs, eye pain, sudden vision changes, headache that is severe or doesn’t go away, stiff/painful neck.Use of this medication for prolonged or repeated periods may result in oral thrush or a new yeast infection. Contact your doctor if you notice white patches in your mouth, a change in vaginal discharge, or other new symptoms.A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.In the US -Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.In Canada – Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
Before taking metronidazole, tell your doctor or pharmacist if you are allergic to it; or to other antibiotics (such as tinidazole); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.Before using this medication, tell your doctor or pharmacist your medical history, especially of: liver disease, kidney disease, certain blood disorders (low blood cell counts).People with a rare genetic disorder (Cockayne syndrome) may be at risk for very serious liver disease if they use metronidazole. Discuss the risks and benefits with your doctor. If metronidazole is used, your doctor will check your liver function. Get medical help right away if you have any signs of liver disease during treatment (such as nausea/vomiting that doesn’t stop, loss of appetite, severe stomach/abdominal pain, yellowing eyes/skin, dark urine).Avoid alcoholic beverages and products containing propylene glycol while taking this medication and for at least 3 days after finishing this medicine because severe stomach upset/cramps, nausea, vomiting, headache, and flushing may occur.This drug may make you dizzy. Alcohol or marijuana (cannabis) can make you more dizzy. Do not drive, use machinery, or do anything that needs alertness until you can do it safely. Talk to your doctor if you are using marijuana (cannabis).Metronidazole may cause live bacterial vaccines (such as typhoid vaccine) to not work as well. Do not have any immunizations/vaccinations while using this medication unless your doctor tells you to.Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.This medication passes into breast milk. Discuss the risks and benefits with your doctor before breast-feeding. If you are prescribed the single-dose treatment, your doctor may direct you to stop breast-feeding for a short time after the dose. Consult your doctor for more details.
See also Precautions section.
Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor’s approval.Some products that may interact with this drug include: alcohol-containing products (such as cough and cold syrups, aftershave), products containing propylene glycol, lopinavir/ritonavir solution, lithium.Do not take metronidazole if you are also taking disulfiram or if you have taken disulfiram within the last 2 weeks.This medication may interfere with certain lab tests, possibly causing false test results. Make sure lab personnel and all your doctors know you use this drug.
If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include: nausea, vomiting, unsteadiness.
Do not share this medication with others.If you are being treated for a certain infection (trichomoniasis), all sexual partners may also need to be treated to avoid re-infection. During treatment, avoid sexual intercourse, or always use a latex or polyurethane condom.This medication has been prescribed for your current condition only. Do not use it later for another infection unless your doctor tells you to.If you are taking this medication for a longer time, lab tests (such as blood cell counts) may be done while you are taking this medication. Keep all medical and lab appointments. Consult your doctor for more details.
If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Take your next dose at the regular time. Do not double the dose to catch up.
Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.
Information last revised January 2020. Copyright(c) 2020 First Databank, Inc.
Flagyl oral disclaimer IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this
Can You Smoke Weed While on Antibiotics?
Some things don’t mix. With this in mind, it is always important to be aware and cautious of what you’re taking when on any sort of medication, since certain medicines will have a negative or more enhanced reaction when taken with another substance. Case in point: When you’re fighting off a bacterial infection, doctors generally prescribe antibiotics, which come along with some strict rules. But almost never addressed is an important question: can you smoke weed while taking those antibiotics?
High Times decided to ask Terry Roycroft, the president of Canada’s Medicinal Cannabis Resource Centre Inc. (MCRCI), which works with doctors who have a special understanding of the medical applications of cannabis. Roycroft has studied marijuana and its effects for over a decade and is highly passionate about advancing public knowledge of the plant. Thankfully, according to him, taking antibiotics and smoking marijuana may not be as harmful to an individual as one would initially think.
How Harmful Are Interactions?
“There’s a number of drug interactions for numerous everyday things. For example, even with caffeine, there are 82 drug interactions out there and some of them are moderately severe to severe,” Roycroft explains.
According to the UK’s National Health Service, it’s “sensible” to stay away from drinking when taking antibiotics, although only two medications call for completely avoiding alcohol altogether: metronidazole and tinidazole. Even something as harmless as grapefruit can have a negative interaction with antibiotics. This piece of fruit can interfere with the metabolism of a number of medications, including some antibiotics used to treat certain respiratory, stomach and other infections. In fact, Roycroft says that they began using grapefruit as a guide for cannabis.
“The reality is that there [are] very little interactions with cannabis. In fact, the antibiotics are not on the contraindicator list [the list of symptoms or conditions that makes a procedure inadvisable] with cannabis,” Roycroft says.
Any interactions that have been identified are very mild — and, in fact, doctors are currently testing to see if some antibiotics work more favorably mixed with marijuana.
“For instance, when we’re treating someone that’s on pain medication and we introduce cannabis, we will cut their [antibiotic] dose in half immediately and they get the same benefits as they would, and the same reactions as if they were taking the full amount.”
Although there may be very mild interactions, effects may still be felt by those who mix the two. According to Jessie Gill, a medical nurse who specializes in medical marijuana, using some macrolide antibiotics, such as troleandomycin, could potentially interact with marijuana.
“Marijuana inhibits a specific enzyme in the liver, cytochrome p450. This enzyme is used by many medications – including some antibiotics,” Gill wrote on Quora.
“What this means is that the effect of the medications will be increased. That also means you’d be at a higher risk of experiencing side effects and adverse reactions from the antibiotics.”
What About Taking CBD?
Interestingly, studies have shown that CBD may, in fact, actually have antibiotic properties. Newsweek reports that Australian scientists have discovered that cannabidiol killed numerous strains of bacteria, including some that have been notoriously resistant to traditional antibiotics. But so far, it still seems like CBD has a long way to go, in terms of replacing antibiotics altogether.
“We still don’t know how it works, and it may have a unique mechanism of action given it works against bacteria that have become resistant to other antibiotics, but we still don’t know how,” Mark Blaskovich, senior research chemist at the Centre for Superbug Solutions, told Newsweek.
“So far, we have only shown it works topically, on the skin surface. To be really useful, it would be good if we could show that it treated systemic infections e.g. pneumonia, or complicated tissue infections, where you have to give it orally or by intravenous dosing. A very preliminary study didn’t show that it works in these more difficult models.”
So, Should You Consume Cannabis on Antibiotics?
All in all, Roycroft says there’s really no issue with mixing cannabis and antibiotics. You may just experience increased side effects of the medication.
“At the Medicinal Cannabis Resource Centre Inc., we have patients on antibiotics and we would not tell them to stop their cannabis use,” Roycroft says.
As for other doctors, they will sometimes use grapefruit as a guide for cannabis. If there is a contraindication with grapefruit, then you may not want to mix cannabis with the medication.
If it is still an issue you’re concerned about, ask your doctor what they recommend — after all, there’s nothing wrong with receiving additional medical advice from a professional.
We know we're not supposed to drink alcohol while taking antibiotics. But what about consuming cannabis? Here's what the experts say.