Categories
BLOG

lsa morning glory seeds dosage

Lsa morning glory seeds dosage

WARNING: Always start with lower doses due to differences between individual body weight, tolerance, metabolism, and personal sensitivity. See responsible use section.

DISCLAIMER: PW’s dosage information is gathered from users and resources for educational purposes only. It is not a recommendation and should be verified with other sources for accuracy.

Lysergic acid amide (also known as ergine, d-lysergic acid amide, d-lysergamide, and LSA) is a naturally-occurring psychedelic substance of the lysergamide class. LSA is an ergot alkaloid and the main psychoactive constituent of morning glory seeds. [ citation needed ] LSA is chemically related to LSD and is said to produce similar effects, although the extent to which it does is unclear.

LSA was first described in 1932 as part of an investigation into the alkaloids found in ergot. [1] In 1947, it was synthesized and tested for human activity by Albert Hofmann. The intramuscular administration of a 500 microgram dose produced a “tired, dreamy state with an inability to maintain clear thoughts.” [2] In 1970, LSA was detected as a constituent in Hawaiian baby woodrose seeds, which were being ground up into capsules and sold on the street as “mescaline”. [3] Today, LSA is typically consumed via morning glory and Hawaiian baby woodrose seeds. [4]

User reports describe the effects of LSA as primarily sedating and dream-like, with a mild to moderate psychedelic component. The psychedelic effects of LSA occur inconsistently and are not directly comparable to the effects of classical psychedelics like LSD, psilocybin mushrooms, or mescaline. LSA is described as primarily bodily and cognitive with little visual effects. Many users report serious nausea and bodily discomfort (“body load”) when taking LSA-containing seeds.

Like other psychedelics, LSA is not considered to be addictive. [5] However, adverse reactions such as severe anxiety, paranoia, and psychosis are always possible, particularly among those who are predisposed to psychiatric disorders. [6] It is therefore highly advised to use harm reduction practices if using this substance.

Contents

  • 1 Chemistry
  • 2 Pharmacology
  • 3 Subjective effects
    • 3.1 Physical effects
    • 3.2 Visual effects
      • 3.2.1 Enhancements
      • 3.2.2 Distortions
      • 3.2.3 Geometry
      • 3.2.4 Hallucinatory states
    • 3.3 Cognitive effects
    • 3.4 Auditory effects
    • 3.5 Transpersonal effects
    • 3.6 Combination effects
    • 3.7 Experience reports
  • 4 Natural plant sources
    • 4.1 Morning glory seeds (MGS)
    • 4.2 Hawaiian baby woodrose seeds (HBWR)
    • 4.3 Preparation methods
  • 5 Toxicity and harm potential
    • 5.1 Vasoconstriction
    • 5.2 Dependence and abuse potential
    • 5.3 Dangerous interactions
    • 5.4 Other interactions
  • 6 Legal status
  • 7 See also
  • 8 External links
    • 8.1 Discussion
  • 9 References

Chemistry

LSA, or d-lysergic acid amide, is an organic alkaloid belonging to the lysergamide class. The chemical structure of LSA contains a core structure of lysergic acid with an amine functional group bound to RN. The structure of lysergic acid is composed of a bicyclic hexahydroindole fused to a bicyclic quinoline group (lysergic acid). At carbon 8 of the quinoline, an acetamide group is bound. LSA is additionally substituted at carbon 6 with a methyl group.

LSA is a chiral compound with two stereocenters at R5 and R8. LSA, also called (+)-D-LSA, has an absolute configuration of (5R, 8R). The three other stereoisomers of LSA do not have psychoactive properties. LSA is structurally analogous to LSD, with the exception being that LSA lacks the diethyl substitution of LSD at RN of its carboxamide group. It can be used as a precursor to LSD.

Pharmacology

LSA’s psychedelic effects are believed to come from its efficacy at the 5-HT2A receptor as a partial agonist. However, the role of these interactions and how they result in the psychedelic experience remains the subject of scientific investigation.

The notion that LSA is the primary psychedelic constituent in morning glory and Hawaiian baby woodrose seeds has been challenged as the effects of isolated synthetic LSA are reported to be only slightly psychedelic in nature. Therefore, it has been proposed that the overall experience may possibly be produced by a mixture of various lysergamide alkaloids (including iso-LSA and LSH) within these plant materials instead of a single psychoactive compound.

Subjective effects

Disclaimer: The effects listed below cite the Subjective Effect Index (SEI), a literature based on anecdotal reports and the personal experiences of PsychonautWiki contributors. As a result, they should be treated with a healthy amount of skepticism. It is worth noting that these effects will not necessarily occur in a consistent or reliable manner, although higher doses are more likely to induce the full spectrum of effects. Likewise, adverse effects become much more likely with higher doses and may include serious injury or death.

Physical effects

    • Sedation – LSA is predominantly sedating; however, this can be setting dependent. For example, when taken in settings with large amounts of stimuli or during physically strenuous activities such as walking, running, climbing or dancing, LSA is capable of becoming stimulating and energetic. In contrast, when taken in calm environments such as darkened rooms with comfortable seating, it tends to be relaxing, sedating.
    • Spontaneous bodily sensations – The “body high” of LSA can be described as a mild yet pleasurable and soft tingling sensation. This is largely noticed in high doses and is accompanied by strong waves of physical euphoria which are usually manifested spontaneously at different unpredictable points throughout the trip but can also maintain a consistent presence. Compared to LSD, the physical effects of LSA tend to predominate the experience relative to its visual and cognitive effects.
      • Perception of bodily heaviness
      • Physical euphoria – This effect is reported to be more readily able to be produced by LSA than LSD. However, it can be masked by strong, uncomfortable feelings of nausea and vasoconstriction, particularly when LSA-containing seeds are consumed directly before any extraction has been performed.
    • Motor control loss – This effect becomes far more present at high doses than lower doses. It can be compared to the loss of motor control experienced with alcohol-induced inebriation and is strengthened by the perception of bodily heaviness.
    • Temperature regulation suppression [citation needed]
    • Nausea – The nauseating effects of LSA is thought to be mostly caused by the other components of the seeds (e.g. morning glory, Hawaiian baby woodrose, etc.) and not LSA itself. Various extraction methods can be used to significantly reduce if not eliminate the nausea that can be produced by this substance. Anecdotal reports also suggest that ginger tea or cannabis may be helpful in counteracting nausea.
    • Vasoconstriction [citation needed] – LSA is commonly reported to produce strong and pronounced feelings of vasoconstriction. This varies in its intensity between individuals but is often considered moderately to extremely uncomfortable in comparison to other psychedelics. This effect is commonly reported to cause joint and limb pains.
    • Increased heart rate
    • Increased blood pressure or Decreased blood pressure [citation needed] – LSA has been reported as being capable of producing both an increase and a decrease in blood pressure, sometimes alternating at different points in the experience, such as during the come up or offset, although it is unclear how much of this is dependent on the seeds and variations in alkaloid contents.
    • Muscle contractions & Muscle relaxation
    • Muscle spasms
    • Dehydration
    • Dizziness
    • Headaches [citation needed]
    • Appetite suppression
    • Gustatory enhancement
    • Orgasm suppression
    • Excessive yawning
    • Pupil dilation
    • Photophobia
    • Increased perspiration
    • Difficulty urinating

Visual effects

  • The visual effects of LSA are mostly present when large doses have been consumed. When compared to LSD and psilocin, the visual effects of LSA are proportionally mild in comparison to the intensity of its accompanying cognitive and physical effects.
Enhancements
  • Colour enhancement
  • Pattern recognition enhancement
  • Visual acuity enhancement
  • Frame rate enhancement
Distortions

The visual distortions and alterations are significantly more simplistic than open eye distortions found with other psychedelics. The effects experienced are detailed below:

  • Depth perception distortions
  • Drifting(melting, breathing, morphing and flowing) – In comparison to other psychedelics, this effect can be described as mild but highly detailed and cartoon-like in appearance. The distortions are fast yet smooth in motion and fleeting in permanence. This is an inconsistently manifested effect with some people never reporting such effects.
  • Colour shifting
  • Tracers
  • Scenery slicing
  • Symmetrical texture repetition
Geometry

The visual geometry produced by LSA can be described as more similar in appearance to that of 4-AcO-DMT and ayahuasca than LSD or 2C-B. It can be described through its variations as primarily intricate in complexity, abstract in form, organic in appearance, unstructured in organization, dimly lit, multicolored in scheme, glossy in shading, soft in edges, small in size, slow in speed, smooth in motion, rounded in corners, non-immersive in depth and consistent in intensity. At higher doses, it is significantly more likely to produce 8B geometry over 8A geometry.

Hallucinatory states

LSA is capable of consistently producing a full range of high-level hallucinatory states when it is taken in large doses. However, the doses required to achieve these states are likely to produce very uncomfortable, and potentially dangerous, side effects. These states include:

  • Transformations – These are extremely common within LSA and partially follow the content of the user’s current thought process.
  • Internal hallucination (autonomous entities; settings, sceneries, and landscapes; perspective hallucinations and scenarios and plots) – Unlike LSD, LSA consistently produces moderate to high level hallucinatory states in high doses. This particular effect can be compared to a lucid dream state. The hallucinations are more common within dark environments and can be comprehensively described through their variations as lucid in believability, interactive in style, new experiences in content, controllable and almost exclusively of a personal, religious, spiritual, science-fiction, fantasy, surreal, nonsensical or transcendental nature in their overall theme.
  • External hallucination (autonomous entities; settings, sceneries, and landscapes; perspective hallucinations and scenarios and plots) – This effect occurs far more rarely and infrequently than with other hallucinogens. However, they can occasionally occur at heavier dosages. They can be described through their variations as lucid in believability, autonomous in controllability, and solid in style.
  • Peripheral information misinterpretation

Cognitive effects

  • The cognitive effects of LSA are described by many as extremely relaxing yet lucid and clear-headed in style when compared to other commonly used psychedelics such as LSD or psilocin. Although it is primarily sedating, it can produce fast-paced bursts of thought and stimulation at random intervals. LSA produces a large number of psychedelic cognitive effects. The most prominent of these typical effects include:
    • Analysis enhancement – This effect is introspection dominant.
    • Anxiety or Anxiety suppression
    • Conceptual thinking
    • Cognitive euphoria
    • Déjà vu
    • Delusion
    • Emotion enhancement
    • Empathy, affection and sociability enhancement
    • Increased music appreciation – Listening to music can strongly intensify the overall experience.
    • Immersion enhancement
    • Language suppression – Mild compared to language suppression on classical psychedelics like LSD.
    • Increased sense of humor
      • Laughter fits
    • Memory suppression
      • Ego death
    • Mindfulness
    • Novelty enhancement
    • Rejuvenation
    • Autonomous voice communication
    • Thought acceleration
    • Thought connectivity
    • Thought loops
    • Time distortion
    • Wakefulness

Auditory effects

    • Auditory enhancement
    • Auditory distortion
    • Auditory hallucinations

Transpersonal effects

    • Spirituality enhancement
    • Existential self-realization – This effect is less common and reproducible than it is with classical psychedelics like LSD, psilocybin mushrooms, and mescaline.
    • Unity and interconnectedness

Combination effects

  • Cannabis – Cannabis can immensely intensify the sensory and cognitive effects of LSA. Extreme caution is advised when mixing these substances as it can significantly increase the chances of a negative psychological reaction like anxiety, confusion and psychosis. Those who use this combination are advised to start off with only a fraction of their usual cannabis dose and take long breaks between hits in order to avoid a negative reaction.
  • Dissociatives – Dissociatives greatly enhance the cognitive, visuals and general hallucinatory effects of LSA. Dissociative-induced holes, spaces, and voids while under the influence of LSA have significantly more vivid visuals than dissociatives alone, as well as more intense internal hallucinations and correspondingly increased risk of confusion, delusions and psychosis.
  • Alcohol – Alcohol’s central depressant effects can be used to reduce some of the anxiety and tension produced by LSA. However, alcohol can cause dehydration, nausea and physical fatigue which can significantly worsen the experience. If using alcohol, it is advised to pace oneself and drink just a fraction of the usual amount.
  • Benzodiazepines – Depending on the dose, benzodiazepines can slightly to completely reduce the intensity of the cognitive, physical and visual effects of an LSA trip. They are very efficient at stopping “bad trips” at the cost of amnesia and reduced trip intensity. Caution is advised when acquiring them for this purpose as they are very easy to abuse.
  • Psychedelics – When used in combination with other psychedelics, each substance’s physical, cognitive and visual effects intensify and synergize strongly. The synergy between those substances is unpredictable, and for this reason generally not advised. If choosing to combine psychedelics, it is recommended to start with significantly lower dosages than one would take for either substance individually.

Experience reports

Anecdotal reports which describe the effects of this compound within our experience index include:

Additional experience reports can be found here:

Natural plant sources

Although LSA is illegal in some countries, various seeds which contain it are readily available in many gardening stores. However, the seeds from commercial sources are often coated in some form of pesticide or methylmercury which can result in extreme nausea and bodily discomfort if ingested. Methods for cleaning or de-coating the seeds are available, but are typically ineffective. Typically, the seeds have a earthy, dirt-like taste that can linger. Seeds that have any other flavor should be spit out so as to avoid hazardous coatings. The seed types listed below can be purchased without pesticide coatings online.

Morning glory seeds (MGS)

The seeds of many species of morning glory are known to contain lysergamide alkaloids such LSA. [7] Typical oral doses of morning glory seeds are as follows:

  • Threshold:20 – 50 seeds / 1.5 g
  • Light:50 – 100 seeds / 1.5 – 3 g
  • Common:100 – 250 seeds / 3 – 6 g
  • Strong:250 – 400 seeds / 6 – 10 g
  • Heavy:400 seeds + / 10 g +

Hawaiian baby woodrose seeds (HBWR)

Hawaiian baby woodrose is a perennial climbing vine that is native to the Indian subcontinent and has since been introduced to numerous areas worldwide including Hawaii, Africa and the Caribbean. Its seeds may be consumed for their various lysergamide alkaloids such as LSA. [8] Typical oral doses for Hawaiian baby woodrose seeds are as follows:

  • Threshold:1 – 3 seeds
  • Light:3 – 5 seeds
  • Common:5 – 7 seeds
  • Strong:7 – 12 seeds
  • Heavy:12 seeds +

Preparation methods

LSA containing seeds can be prepared using a number of methods. Some of these methods are listed in our tutorial index and include:

Toxicity and harm potential

This toxicity and harm potential section is a stub.

As such, it may contain incomplete or even dangerously wrong information. You can help by expanding or correcting it.
We also recommend that you conduct independent research and use harm reduction practices when using this substance.

The toxicity and long-term health effects of recreational LSA use have not been studied in any scientific context and the exact toxic dose is unknown.

Anecdotal evidence suggests that there are no negative health effects attributed to simply trying LSA by itself at low to moderate doses and using it very sparingly (but nothing can be completely guaranteed). Independent research should always be done to ensure that a combination of two or more substances is safe before consumption.

It is strongly recommended that one use harm reduction practices when using this substance.

Vasoconstriction

LSA should not be used regularly for long periods of time. When used repeatedly over a short period of time, LSA’s vasoconstrictive effects build up while the psychoactive effects get weaker. A common sign of vasoconstriction build up can be described as a feeling of painful or uncomfortable legs. [9] This happens as a result of an insufficient amount of blood getting to the muscles. The upper leg muscles are the largest, most energy consuming muscles in the body and will feel sore if blood flow to them is lowered even slightly.

When HBWR, morning glory seeds or pure LSA seeds are consumed and sore legs are experienced, a break has been reported to be helpful. With LSA it can take up to 3 days of abstinence to get back to vasoconstriction baseline.

Dependence and abuse potential

LSA is considered to be non-addictive with a low abuse potential. There are no literature reports of successful attempts to train animals to self-administer LSA, an animal model predictive of abuse liability, indicating that it does not possess the necessary pharmacology to either initiate or maintain dependence. [ citation needed ] There is virtually no withdrawal syndrome when use is stopped.

Tolerance to the effects of LSA forms almost immediately after ingestion. After that, it takes about 7 days for the tolerance to return to baseline (in the absence of further consumption). LSA produces cross-tolerance with all psychedelics, meaning that after the use of LSA all psychedelics will have a reduced effect.

Dangerous interactions

Although many psychoactive substances are reasonably safe to use on their own, they can quickly become dangerous or even life-threatening when combined with other substances. The list below includes some known dangerous combinations (although it cannot be guaranteed to include all of them). Independent research (e.g. Google, DuckDuckGo) should always be conducted to ensure that a combination of two or more substances is safe to consume. Some interactions listed have been sourced from TripSit.

  • Lithium – Lithium is commonly prescribed for the treatment of bipolar disorder. There is a large body of anecdotal evidence that suggests taking it with psychedelics significantly increases the risk of psychosis and seizures. As a result, this combination is strictly discouraged.
  • Cannabis – Cannabis may have an unexpectedly strong and unpredictable synergy with the effects of LSA. Caution is advised with this combination as it can significantly increase the risk of adverse psychological reactions like anxiety, paranoia, panic attacks, and psychosis. Users are advised to start off with only a fraction of their normal cannabis dose and take long breaks between hits to avoid unintentional overdose.
  • Stimulants – Stimulants like amphetamine, cocaine or methylphenidate affect many parts of the brain and alter dopaminergic function. This combination can increase the risk of anxiety, paranoia, panic attacks, and thought loops. This interaction may also result in an elevated risk of mania and psychosis. [citation needed]
  • Tramadol – Tramadol is well-documented to lower the seizure threshold [10] and psychedelics may act to trigger seizures in susceptible individuals. [citation needed]

Lysergic acid amide (also known as ergine, d-lysergic acid amide, d-lysergamide, and LSA) is a naturally-occurring psychedelic substance of the lysergamide class. LSA is an ergot alkaloid and the main psychoactive constituent of morning glory seeds.[citation needed] LSA is chemically related to LSD and is said to produce similar effects, although the extent to which it does is unclear.

Microdosing Part 4 – LSA Seeds: The Natural LSD?

Microdosing – taking a little bit of a psychedelic substance to become more creative – began with LSD. That is rather surprising since LSD is extremely concentrated. For that reason, the microdose is very difficult to measure. The synthetic substance cannot be obtained legally in any case which makes you wonder whether there might not be better alternatives.

In this final part of a series about microdosing with various psychedelic smart drugs, we examine the history of microdosing with LSD and the natural and legal alternative of LSA which is found in Hawaiian Baby Woodrose seeds and Morning Glory seeds.

  • Part 1: Magic Truffles
  • Part 2: Ayahuasca
  • Part 3: Peyote & San Pedro Cacti
  • Part 4: LSA Seeds. The Natural LSD?

All the positives without the negatives. That might be one way of describing microdosing. You take a little bit (approximately one-tenth of a mild dosage) of a psychedelic smart drug in the hope of looking at a problem differently from how you usually look at it, for example. And all without seeing weird people, colours or patterns everywhere. How do you discover that this is possible anyway?

‘Not much is happening’

Just imagine: at some point you take too little of magic truffles or LSD to really notice any effect. By effect we mean experiencing all the crazy stuff. Meetings with strange beings, out-of-body experiences, talking to objects – you name it. Then we are talking about a high-level trip. Does nothing at all happen to you? In that case, you have probably:

  • Eaten too much – psychedelics are best taken on an empty stomach
  • Incorrect dosage for your body weight
  • Underestimated the dosage – next time take a bit more
  • Accidentally taken in effect an actual microdose – an imperceptible quantity of a psychedelic substance

How Microdosing Began

This is exactly how microdosing was ‘discovered’: by testing out taking tiny amounts of LSD for a few consecutive days. In the 1960s, LSD was popularised by the counterculture. Hippies sat and tripped in the park while listening to their favourite artists who in turn played music that was probably written under the influence of LSD.

But LSD and shrooms were not just popular with hippies. In the beginnings of Silicon Valley as well, where everything has to become smaller and more powerful, they got LSD out of the cupboard in order to gain new insights and make the impossible feasible. The advantage of LSD as a synthetic means of tripping is that the effect can be properly determined by fixing the dosage of LSD-25 very accurately. The disadvantage is that this goes on under uncontrolled conditions in which you are at the mercy of the dealer and have to take his word for it that a stamp contains that amount of LSD.

Is LSD legal?

LSD is not legal in the Netherlands and as far as we know in no other country either. In the Netherlands, LSD is on Schedule 1 of the Opium Act and is therefore prohibited. The question is whether there is an alternative that is actually obtainable legally or perhaps a natural drug that is easy to cultivate.

LSD Alternatives

There are plenty of hallucinogenic substances that occur in nature. In this series, we have already discussed a few of them. And yet, experienced psychonauts firmly believe that an LSD trip is unique. For starters, an LSD trip lasts for up to 4 hours longer than with shrooms or magic truffles – up to 12 hours. But this series of articles isn’t about tripping. Would the freely available alternatives that exist in some countries be any different in terms of microdosing LSD?

Time to check out nature. There are a number of plants in nature (and perhaps in your granny’s flower bed) that produce, among other things, LSA. LSA stands for lysergic acid amide and is used to make LSD (lysergic acid diethylamide) in the lab. LSA is itself pyschoactive as well but to a lesser extent. In terms of feeling and visuals, a trip on LSA is comparable to one on LSD, only it’s a bit more restrained. How closely the trips resemble each other (or not) depends on the comparative material and the nature of the trips of the psychonaut who describes them. In our opinion, it doesn’t make a lot of difference for microdosing. All the effects are similar.

Hawaiian Baby Woodrose [Argyreia nervosa]

The Hawaiian Baby Woodrose (HBW) is a climber that can overrun your garden in no time at all with magnificently coloured flowers. The seeds contain LSA, lysergol and ergine which all contribute to the effects if the seeds are consumed.

There is around 0.25 mg of LSA in a single seed. That corresponds to approximately 25 µg LSD – which would be a low dosage. LSA has one tenth of the hallucinogenic power of LSD. Do you want to have a solid trip? Six seeds will get you nicely on your way. Because HBW seeds are so potent, we don’t recommend them for microdosing. For a microdose, you would only need to take just one tenth of a seed!

For advice on usage, read the product description for Hawaiian Baby Woodrose seeds.

Morning Glory [Ipomoea tricolor] / [Ipomoea violacea]

Morning Glory is a collective name for a whole range of plants that strongly resemble each other. It is claimed by some that there are a good 1,000 varieties named Morning Glory. Many of these attractive trumpet-shaped flowers produce seeds with LSA. In the case of the Mexican Morning Glory ((tricolor/violacea), we know that as well as the seeds, the lianas, flowers and leaves all contain alkaloids, including LSA. A handful of varieties are also actually cultivated as psychedelics.

One seed from the tricolor variant Heavenly Blue is not enough for tripping. To put it in even more perspective – before you would notice any visual distortions, you would have to eat 20 to 50 seeds. And yet this is the most commonly used and one of the strongest morning glory seeds. For a proper psychedelic trip, expect to take upwards of 250 seeds!

Because the LSA concentration is fairly low, microdosing is again a valid option. For example, 10 seeds of the Heavenly Blue makes for a very good dosage.

Nausea

Both morning glory and hawaiian baby woodrose seeds naturally contain substances which can produce nausea. It’s a misunderstanding that this unpleasantness is caused by the LSA. However, there are other substances such as glycosides in the seeds which can cause stomach cramps and/or nausea. Fortunately though these pass more quickly than the positive effects last for. And the less you take, the less the side effects will bother you. Good news for microdosing, then!

Conclusion

Is microdosing with morning glory or hawaiian baby woodrose a good idea? Morning Glory Heavenly Blue and a couple of other varieties contain a good amount of LSA with which to microdose. Hawaiian Baby Woodrose seeds are a good deal stronger and therefore less suitable for taking during work to get you thinking in another direction. You’re better off taking HBW seeds therefore when you’re planning to spend a couple of hours communing with nature. Try the Morning Glory LSA seeds out once and let us know about your microdosing experiences in the product feedback!

LSA: the natural alternative to LSD? Can you microdose with Morning Glory and Hawaiian Baby Woodrose seeds?